{"created":"2023-09-29T06:05:11.930106+00:00","id":2000008,"links":{},"metadata":{"_buckets":{"deposit":"86e93ac3-0f73-4007-9758-80fc139769b8"},"_deposit":{"created_by":4,"id":"2000008","owner":"4","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"2000008"},"status":"published"},"_oai":{"id":"oai:yamazaki-u.repo.nii.ac.jp:02000008","sets":["7:1695869315434"]},"author_link":[],"control_number":"2000008","item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-03-26","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"23","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"動物研究"},{"bibliographic_title":"Studies in Animals","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"毛色は外観から容易に判別できる遺伝的形質である。毛色は色素細胞において産生する2種類のメラニン色素、ユーメラニンとフェオメラニンにより作られる。ユーメラニンは黒/茶色を、フェオメラニンは赤/黄色を成す。毛色には100以上の遺伝子が関与することが示されている。なかでもメラノコルチン1型受容体（MC1R）はよく研究され、その受容体をコードするMC1R遺伝子は毛色を決める関連遺伝子として重要な役割をもつ。また、MC1R遺伝子遺伝子変異による毛色と生理機能の関連や、MC1R遺伝子多型に隠された家畜化の過程と毛色の関係も示されている。\n本稿では、歴史的にさまざまな動物種を取り上げ研究されてきたMC1Rに注目し、哺乳動物における毛色とMC1R遺伝子の変異との関係について最近の知見を解説する。特に具体的にMC1R遺伝子変異箇所と多様な毛色の関係について、愛玩動物（イヌ、ネコ、ウサギ、ウマ）、畜産動物（ウシ、ブタ、ヒツジ、ヤギ、アカキツネ、トナカイ）、野生動物（ホッキョクキツネ、ネコ科の動物のジャガーやじゃがらんでぃ、ポケットマウス）を紹介する。","subitem_description_type":"Abstract"}]},"item_10002_full_name_3":{"attribute_name":"著者（英）","attribute_value_mlt":[{"names":[{"name":"Oguro-Okano Mieko","nameLang":"en"}]}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"ヤマザキ動物看護大学"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2434-5709","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小黒（岡野）美枝子","creatorNameLang":"ja"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-10-04"}],"displaytype":"detail","filename":"哺乳動物の毛色に関連するメラノコルチン1型受容体遺伝子の多様性","licensetype":"license_8","version_id":""},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2023-09-29"}],"filename":"哺乳動物の毛色に関連するメラノコルチン1型受容体遺伝子の多様性.pdf","filesize":[{"value":"2.2 MB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://yamazaki-u.repo.nii.ac.jp/record/2000008/files/哺乳動物の毛色に関連するメラノコルチン1型受容体遺伝子の多様性.pdf"},"version_id":"695b5160-da86-4a96-817f-7d126717d51f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"毛色","subitem_subject_scheme":"Other"},{"subitem_subject":"メラノコルチン1型受容体","subitem_subject_scheme":"Other"},{"subitem_subject":"遺伝子","subitem_subject_scheme":"Other"},{"subitem_subject":"MC1R","subitem_subject_scheme":"Other"},{"subitem_subject":"哺乳動物","subitem_subject_scheme":"Other"},{"subitem_subject":"coat color","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"melanocortin type 1 receptor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gene","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"MC1R","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"mammals","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"哺乳動物の毛色に関連するメラノコルチン1型受容体遺伝子の多様性－イヌ、ネコ、ウサギ、ウマ、ブタ、ウシ、ヒツジ、ヤギ、キツネ、トナカイ、ジャガー、ジャガランディ、ポケットマウス－","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"哺乳動物の毛色に関連するメラノコルチン1型受容体遺伝子の多様性－イヌ、ネコ、ウサギ、ウマ、ブタ、ウシ、ヒツジ、ヤギ、キツネ、トナカイ、ジャガー、ジャガランディ、ポケットマウス－","subitem_title_language":"ja"}]},"item_type_id":"10002","owner":"4","path":["1695869315434"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-10-02"},"publish_date":"2023-10-02","publish_status":"0","recid":"2000008","relation_version_is_last":true,"title":["哺乳動物の毛色に関連するメラノコルチン1型受容体遺伝子の多様性－イヌ、ネコ、ウサギ、ウマ、ブタ、ウシ、ヒツジ、ヤギ、キツネ、トナカイ、ジャガー、ジャガランディ、ポケットマウス－"],"weko_creator_id":"4","weko_shared_id":-1},"updated":"2023-10-03T06:59:55.615403+00:00"}